Orlos is an over-the-counter weight loss aid containing 60 mg of orlistat, a lipase inhibitor that reduces fat absorption from the diet. It's designed for adults with a Body Mass Index (BMI) of 28 or higher and should be used alongside a reduced-calorie, low-fat diet and regular exercise. Orlos works by blocking about 25–30% of dietary fat from being absorbed, allowing it to pass through the body undigested .
Common (may affect up to 1 in 10 people):
Oily or fatty stools
Flatulence with oily discharge
Urgent or increased bowel movements
Loose stools or diarrhea
Abdominal pain or discomfort
Rectal pain or discomfort
Serious (seek immediate medical attention):
Signs of liver problems: yellowing of the skin or eyes, dark urine, loss of appetite, or upper right abdominal pain
Signs of kidney stones: severe back pain, blood in urine, or painful urination
Allergic reactions: rash, itching, swelling, or difficulty breathing.
Age and BMI Restrictions: Not suitable for individuals under 18 years or those with a BMI below 28.
Pregnancy and Breastfeeding: Do not use if pregnant, planning to become pregnant, or breastfeeding.
Medical Conditions: Consult a healthcare provider before use if you have conditions like diabetes, kidney disease, thyroid disorders, epilepsy, or malabsorption syndromes .
Vitamin Absorption: Orlos may reduce the absorption of fat-soluble vitamins (A, D, E, K). Consider taking a multivitamin supplement at least 2 hours before or after taking Orlos .
Dietary Fat Intake: High-fat meals can increase gastrointestinal side effects. It's recommended to keep fat intake to about 30% of total daily calories .
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